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Dissolve-It-All — serrapeptase and nattokinase, taken away from food

A systemic enzyme blend in a phthalate-free enteric capsule. The timing instruction is the mechanism, not a suggestion.

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What it is

A systemic enzyme blend containing serrapeptase and nattokinase, in an enteric capsule stated to be phthalate-free.

Why people consider it

Systemic enzymes are a distinct category from digestive enzymes, and the difference is about where they are meant to act.

Digestive enzymes work in the gut, on your meal. Systemic enzymes are intended to be absorbed and act elsewhere, which is why they are taken away from food — a meal in the stomach gives them something to work on and they never get past it.

Serrapeptase and nattokinase are both proteolytic enzymes with reasonably long histories of use and a research literature of their own. People generally arrive at this category having read about one of them specifically.

What makes this one worth a look

Two formulation points that are real rather than marketing.

The enteric coating is functionally necessary here, not a premium feature. These enzymes are proteins, and stomach acid is very good at destroying proteins. Without an enteric coating, substantially less survives to be absorbed. That this one specifies a phthalate-free coating material is a genuine detail — phthalates are a reasonable thing to prefer to avoid, and most products do not say either way.

The usage instruction is specific and published: empty stomach, 8 to 10 oz of water, at least twenty minutes before food or two hours after, not combined with other supplements. That precision is useful, and it is unusual — most products in this category say “take as directed”.

What is missing is activity units. Serrapeptase is measured in SPU and nattokinase in FU, and neither is published, which means you cannot compare this against another brand on strength. That is the one number worth asking for.

Key facts

Price $60
Count 90 per bottle
Cost per unit $0.67
Serving size Manufacturer-stated: 1 or more capsules; timing-based rather than a fixed daily count
Contains Serrapeptase · Nattokinase (soy-free)
Suggested use The manufacturer states: take 1 or more capsules on an empty stomach, at least 20 minutes before a meal or 2 hours after eating, with water only and not alongside food, supplements or medications. Swallow whole; do not chew or open the capsule.
Certificate of analysis Published by the manufacturer
Availability In stock when checked on 2026-10-04

Dissolve-It-All (Systemic Enzymes) — $60 for 90 capsules, about $0.67 each. At one capsule a day, that is the daily cost too.

Who it may suit

  • You specifically want serrapeptase and nattokinase and would rather have them combined than buy two products.
  • You can reliably take something on an empty stomach, away from other supplements.
  • You care about capsule composition — the enteric coating here is stated as phthalate-free.
Less of a fit if…
  • You take blood-thinning medication of any kind. See the note at the top of this page.
  • You want digestive support with meals. That is Digest-It-All, and it is taken the opposite way.
  • You will not remember the timing. Taken with food, this product does not do what it is for.
  • You want to compare enzyme strength against another brand. No activity units are published.

Worth knowing before you buy

What we verified

7 statements on this page are tiered and traced to a source. Manufacturer statements are labelled as manufacturer statements rather than repeated as findings.

Show the evidence table

Where each claim on this page comes from

Every factual statement above is listed here with its source. Rows marked “manufacturer claim” are the manufacturer’s description of its own product, reported without endorsement.

TierClaimKindSource
ENattokinase has documented fibrinolytic and antiplatelet activity.External sourcePeer-reviewed pharmacology literature on nattokinase fibrinolytic activity
Population: Healthy adults and in vitro models; the page states the interaction as a prescriber question rather than an outcome
EEnteric coating is used so that acid-labile enzyme preparations survive gastric pH and reach the small intestine.External sourcePharmacopoeial and peer-reviewed guidance on enteric-coated enzyme preparations
Population: Not a clinical population — formulation science
BThe product is a single 90-capsule variant priced at $60.00 and available at the 2026-10-04 inventory check.SpecificationMitoLife storefront inventory endpoint, retrieved 2026-10-04
BAt $60 for 90 capsules the unit cost is $0.67 per capsule.SpecificationArithmetic from the verified storefront price
BThe Supplement Facts panel is published as an image that could not be read. Two laboratory documents linked from the product page report a protease activity figure in PC units per capsule; no figure is reported for serrapeptase or nattokinase individually. Serrapeptase is conventionally measured in SPU and nattokinase in FU.SpecificationMitoLife product page and linked laboratory documents, retrieved 2026-09-16 (WebFetch extraction; model-summarised, not a direct visual reading of the label image)
AThe manufacturer states the product contains serrapeptase and nattokinase in a phthalate-free enteric capsule, and publishes a suggested use of 1 or more capsules on an empty stomach, at least 20 minutes before a meal or 2 hours after eating, with water only and not alongside food, supplements or medications.Manufacturer statementMitoLife product page and linked laboratory documents, retrieved 2026-09-16 (WebFetch extraction; model-summarised, not a direct visual reading of the label image)
Manufacturer statement, not independently verified.
FOur view: the timing instruction on this product is the mechanism rather than a suggestion, and taking it with a meal wastes the capsule.Our editorial viewEditorial assessment
Our view: this is our editorial judgement, not a finding.
View Dissolve-It-All (Systemic Enzymes) at MitoLife

This link continues to MitoLife.co, where the order is placed. Mito Keys does not sell or ship anything — payment, delivery and returns are handled by MitoLife under their own terms.

Not ready to decide?

That is a reasonable place to stop. If you are still working out whether this category is for you at all, the comparison covers what these products do, how they differ, and when neither is the answer.

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